May 3, 2010 in Employee Drug Testing Information
Adulteration is the intentional tampering with a urine sample by the donor to avoid detection of illicit drug use. Successful adulteration produces a false-negative drug test result.
Adulterants have often been used to mask the presence of an illicit drug and thus cheat a drug test. Because most urine collection procedures do not involve direct supervision, it is possible to add adulterants after specimen collection. Household chemicals, such as bleach, acid, vinegar, lemon juice, eye drops and table salt are routinely used to beat drug tests. These agents can cause false negative test results from the immunoassays used in urine drugs of abuse testing. However, specimen integrity tests can detect the presence of such adulterants because of altered pH, specific gravity and/or temperature.
More recently, commercial adulterants with names like Stealth, Klear and Urine Luck have become available on the Internet. These adulterants, when added to urine, can cause false negative results in drugs-of-abuse immunoassays, as well as in some gas chromatography/mass spectrometry (GC/MS) confirmation tests. These commercial adulterants some times cannot be detected by routine specimen integrity testing. Recently, however, spot tests have been described to detect these adulterants.